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What is the difference between "Adequan" and "Legend"?
“Adequan”
is a brand of polysulfated glycosaminoglycan (PSGAG) produced by a division
of Luitpold Pharmaceuticals, Inc. The components that make up “Adequan”
are chemically similar to the glycosaminoglycans in joint cartilage. It
serves as an enzyme inhibitor to decrease or reverse the pathologic processes
caused by trauma to the joint or degenerative joint disease. It improves
joint function by reducing protein levels in the joint fluid and increasing
the hyaluronic acid concentration in the synovial fluid. It is an intramuscular
injection initially given more frequently for establishing the appropriate
concentration in the body (loading dose), but then administered once a month
after the loading dose has been established.
“Legend” is
an injectable solution of hyaluronate sodium produced by Bayer Health Care, LLC. Hyaluronic
acid, a glycosaminoglycan, is the conjugate acid of hyaluronate sodium. Hyaluronic
acid is a naturally occurring substance present in high concentrations in the
joint fluid. Hyaluronic sodium decreases enzyme release and subsequent
degradation of joint integrity, and decreases inflammation in the joint. “Legend”
is an intravenous injection initially given more frequently for establishing
the appropriate concentration in the body (loading dose), but then administered
once a month after the loading dose has been established. |
